Volume 2, Issue 3, August 2017, Page: 97-102
Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice
Mohammad Farhadur Rahman, Department of Chemistry, Bangladesh University of Textiles, Dhaka, Bangladesh
Nargish Jahan Ara, Department of Chemistry, Bangladesh University of Textiles, Dhaka, Bangladesh
Bishnu Pada Dey, Department of Pathology, Bangladesh Sheikh Mujib Medical University, Dhaka, Bangladesh
Mohammad Zakir Sultan, Centre for Advanced Research in Sciences, University of Dhaka, Dhaka, Bangladesh
Received: Jun. 18, 2017;       Accepted: Jun. 29, 2017;       Published: Jul. 31, 2017
DOI: 10.11648/j.ijfsb.20170203.14      View  2670      Downloads  178
Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.
In vivo, Textile Dyes, Coralene Red XF, Remazol Red RR, Toxicity
To cite this article
Mohammad Farhadur Rahman, Nargish Jahan Ara, Bishnu Pada Dey, Mohammad Zakir Sultan, Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice, International Journal of Food Science and Biotechnology. Vol. 2, No. 3, 2017, pp. 97-102. doi: 10.11648/j.ijfsb.20170203.14
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